Scientists discovered a way to transform ordinary tissue into beating heart muscle cells. It could pave the way for new therapeutic approaches for making a damaged heart to repair itself. Scientists used a zebrafish system to develop a small and robust molecule, which can transform stem cells into beating heart muscle cells.The scientists in their experiment found that cardionogen treatment enlarged the zebrafish heart by stimulating production of new cardiac muscle cells from stem cells.
The scientists discovered three structurally related molecules (Cardiongen-1, 2 and3) after screening 4000 compounds. It could promote or inhibit heart formation depending on when they were administered during development.
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